Preparation method of (5-halogenothiazole-2-yl) benzoic acid compounds
The invention discloses a preparation method of (5-halogenothiazole-2-yl) benzoic acid compounds. The method comprises the steps of firstly synthesizing thiazole benzoate compounds by taking 2-bromine thiazole as a raw material, then halogenating and hydr
-
Paragraph 0034; 0035; 0040; 0041
(2017/07/12)
PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS
The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula (I): (A chemical formula should be inserted here - please see paper copy enclosed herewith) (I) which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
-
Page/Page column 130
(2008/06/13)
Cyclic derivatives as modulators of chemokine receptor activity
The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.
-
Page/Page column 46
(2008/06/13)
Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis.
-
Page/Page column 45
(2010/02/11)
More Articles about downstream products of 847956-27-8