849021-16-5

Basic information

• Product Name: 4-(4-BROMOPHENYL)PYRAZOLE
• Synonyms: 4-(4-BroMophenyl)-1H-pyrazole;1-Bromo-4-(1H-pyrazol-4-yl)benzene
• CAS NO: 849021-16-5
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.08
• Product Categories: Halides;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 849021-16-5.mol

Chemical Properties

• Melting Point: 208-211°C
• Boiling Point: 390.6°C at 760 mmHg
• Flash Point: 190°C
• Appearance: /
• Density: 1.565g/cm³
• Vapor Pressure: 5.9E-06mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: 2-8°C
• PKA: 13.33±0.50(Predicted)
• CAS DataBase Reference: 4-(4-BROMOPHENYL)PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMOPHENYL)PYRAZOLE(849021-16-5)
• EPA Substance Registry System: 4-(4-BROMOPHENYL)PYRAZOLE(849021-16-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 849021-16-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-(4-Bromophenyl)pyrazole is utilized as a building block in organic synthesis for the creation of diverse chemical compounds. Its unique structure allows for the formation of new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(4-Bromophenyl)pyrazole is employed as a research compound for exploring its potential anti-inflammatory and analgesic properties. Its investigation into these areas is driven by the need for new therapeutic agents to address pain and inflammation.
Used in Neurodegenerative Disease Treatment:
4-(4-Bromophenyl)pyrazole has been studied for its potential use in the treatment of neurodegenerative diseases. Its exploration in this area is motivated by the search for novel compounds that can mitigate the effects of such conditions and improve patient outcomes.
Used as a Reagent in Chemical Reactions:
4-(4-Bromophenyl)pyrazole is also used as a reagent in chemical reactions to introduce its specific moiety into a variety of organic molecules. This application is crucial for the development of new chemical entities with specific functionalities and properties.

InChI:InChI=1/C9H7BrN2/c10-9-3-1-7(2-4-9)8-5-11-12-6-8/h1-6H,(H,11,12)

Upstream product

• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 709648-68-0 2-(4-bromophenyl)malondialdehyde 

Downstream Products

• 1100052-58-1 tert-butyl 4-(4-bromophenyl)pyrazole-1-carboxylate 
• 1607837-73-9 8-(2-amino-3-chloro-5-{4-[1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl]phenyl}pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one 
• 1607837-75-1 8-{2-amino-3-chloro-5-[4-(1-isopropyl-1H-pyrazol-4-yl)-phenyl]pyridin-4-yl}-2,8-diazaspiro[4.5]decan-1-one 
• 756520-56-6 1-(2-(pyrrolidin-1-yl)ethyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole 

Relevant articles and documents

Synthesis, anticancer activity and DNA-binding properties of novel 4-pyrazolyl-1,8-naphthalimide derivatives

A novel series of 4-pyrazolyl-1,8-naphthalimide derivatives have been designed and facilely synthesized. For anticancer activity in vitro, most of the compounds were found to be more toxic against human mammary cancer cells (MCF-7) than human cervical car