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(5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione, also known as aminoglutethimide, is an organic compound with the molecular formula C10H12N2O3. It is a pharmaceutical agent that has been utilized in the treatment of various types of cancer, particularly breast cancer. Aminoglutethimide functions by inhibiting the production of adrenal steroids and blocking the synthesis of estrogen, which can contribute to the slowdown of hormone-dependent tumor growth.

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  • (5E)-5-(aminomethylidene)-1-cyclohexyl-1,3-diazinane-2,4,6-trione

    Cas No: 84941-33-3

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  • 84941-33-3 Structure
  • Basic information

    1. Product Name: (5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione
    2. Synonyms:
    3. CAS NO:84941-33-3
    4. Molecular Formula: C11H15N3O3
    5. Molecular Weight: 237.2551
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 84941-33-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.416g/cm3
    6. Refractive Index: 1.651
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
    10. NIST Chemistry Reference: (5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione(84941-33-3)
    11. EPA Substance Registry System: (5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione(84941-33-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84941-33-3(Hazardous Substances Data)

84941-33-3 Usage

Uses

Used in Anticancer Applications:
Aminoglutethimide is used as an anti-cancer medication for the treatment of breast cancer. It operates by inhibiting the production of adrenal steroids and blocking the synthesis of estrogen, which can help in slowing down the growth of hormone-dependent tumors. It is often administered orally and has been found to be effective when used in combination with other cancer treatments.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (5E)-5-(aminomethylidene)-1-cyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione is used as an active pharmaceutical ingredient for the development of medications targeting hormone-dependent cancers. Its ability to inhibit adrenal steroid production and block estrogen synthesis makes it a valuable compound in the creation of cancer treatment options.

Check Digit Verification of cas no

The CAS Registry Mumber 84941-33-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,9,4 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 84941-33:
(7*8)+(6*4)+(5*9)+(4*4)+(3*1)+(2*3)+(1*3)=153
153 % 10 = 3
So 84941-33-3 is a valid CAS Registry Number.

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