DEALKYLATION OF NUCLEOSIDE ARYLMETHYL 2-CHLOROPHENYL PHOSPHATES: THE 2,4-DINITROBENZYL PROTECTING GROUP
Following a study of the effect of benzyl substitution on the rates of nucleophilic dealkylation of phosphotriesters, 2,4-dinitrobenzyl is proposed as a temporary protecting group for 3'-terminal phosphodiester functions in oligonucleotide synthesis.
Christodoulou, Chris,Reese, Colin B.
p. 951 - 954
(2007/10/02)
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