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4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring. Additionally, it features a tert-butyldimethylsilyloxy group attached to another phenyl ring. This versatile reagent is widely utilized in organic synthesis, particularly for cross-coupling reactions to form carbon-carbon and carbon-heteroatom bonds.

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  • (4'-((TERT-BUTYLDIMETHYLSILYL)OXY)-[1,1'-BIPHENYL]-4-YL)BORONIC ACID

    Cas No: 850380-91-5

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  • 850380-91-5 Structure
  • Basic information

    1. Product Name: 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid
    2. Synonyms: 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid;(4'-((tert-ButyldiMethylsilyl)oxy)-[1,1'-biphenyl]-4-yl)boronic acid
    3. CAS NO:850380-91-5
    4. Molecular Formula: C18H25BO3Si
    5. Molecular Weight: 328.2858
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 850380-91-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid(850380-91-5)
    11. EPA Substance Registry System: 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid(850380-91-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 850380-91-5(Hazardous Substances Data)

850380-91-5 Usage

Uses

Used in Organic Synthesis:
4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid is used as a reagent in organic synthesis for its ability to participate in cross-coupling reactions, which are essential for forming carbon-carbon and carbon-heteroatom bonds. The presence of the boronic acid group makes it a key component in such reactions, facilitating the formation of new chemical linkages.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid is used as a reagent for Suzuki-Miyaura cross-coupling reactions. These reactions are widely employed in the synthesis of complex organic molecules, including those found in pharmaceutical compounds. The versatility of this reagent allows for the creation of a diverse range of drug candidates with potential therapeutic applications.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical industry, 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid is utilized as a reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of agrochemicals. This includes the development of new pesticides, herbicides, and other agricultural chemicals that can improve crop yields and protect against pests.
Used as a Protecting Group in Organic Reactions:
The tert-butyldimethylsilyloxy group in 4-[4-(tert-Butyldimethylsilyloxy)phenyl]phenylboronic acid can be used as a protecting group for alcohols during organic reactions. This allows for selective reactions at other functional groups, enabling chemists to control the reactivity and selectivity of the molecule, which is crucial for the synthesis of complex organic compounds with specific desired properties.

Check Digit Verification of cas no

The CAS Registry Mumber 850380-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,3,8 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 850380-91:
(8*8)+(7*5)+(6*0)+(5*3)+(4*8)+(3*0)+(2*9)+(1*1)=165
165 % 10 = 5
So 850380-91-5 is a valid CAS Registry Number.

850380-91-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names (4'-((tert-Butyldimethylsilyl)oxy)-[1,1'-biphenyl]-4-yl)boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:850380-91-5 SDS

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