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2-(5-Amino-2-chlorophenyl)acetonitrile is a chemical compound characterized by the molecular formula C8H7ClN2. It is a nitrile derivative featuring a phenyl ring with an amino group at the 5-position and a chlorine atom at the 2-position. 2-(5-Amino-2-chlorophenyl)acetonitrile is recognized for its role as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and agrochemical industries, and holds potential as a building block for the production of heterocyclic compounds. Its versatility and applications make it a subject of interest for researchers and industries in organic chemistry.

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  • 850451-72-8 Structure
  • Basic information

    1. Product Name: 2-(5-Amino-2-chlorophenyl)acetonitrile
    2. Synonyms: 2-(5-Amino-2-chlorophenyl)acetonitrile;4-Chloro-3-(cyanomethyl)aniline;5-Amino-2-chlorophenylacetonitrile 95+%
    3. CAS NO:850451-72-8
    4. Molecular Formula: C8H7ClN2
    5. Molecular Weight: 166.60758
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 850451-72-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 341.508 °C at 760 mmHg
    3. Flash Point: 160.338 °C
    4. Appearance: /
    5. Density: 1.283 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(5-Amino-2-chlorophenyl)acetonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(5-Amino-2-chlorophenyl)acetonitrile(850451-72-8)
    11. EPA Substance Registry System: 2-(5-Amino-2-chlorophenyl)acetonitrile(850451-72-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 850451-72-8(Hazardous Substances Data)

850451-72-8 Usage

Uses

Used in Pharmaceutical Industry:
2-(5-Amino-2-chlorophenyl)acetonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties. Its unique structure allows for the creation of a wide range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(5-Amino-2-chlorophenyl)acetonitrile is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides, due to its reactive functional groups that can be further modified to achieve desired biological activities.
Used in Organic Chemistry Research:
2-(5-Amino-2-chlorophenyl)acetonitrile serves as a valuable building block in organic chemistry research, where it is employed for the synthesis of heterocyclic compounds. Its presence in various chemical reactions can lead to the discovery of novel compounds with unique properties and potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 850451-72-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,4,5 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 850451-72:
(8*8)+(7*5)+(6*0)+(5*4)+(4*5)+(3*1)+(2*7)+(1*2)=158
158 % 10 = 8
So 850451-72-8 is a valid CAS Registry Number.

850451-72-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(5-Amino-2-chlorophenyl)acetonitrile

1.2 Other means of identification

Product number -
Other names 4-Chloro-3-(cyanomethyl)aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:850451-72-8 SDS

850451-72-8Relevant articles and documents

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

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, (2008/06/13)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, CSK, JNK1, JNK2, PDGF-R, p38, p70S6K, TGF beta , SRC, EGFR, c-Kit, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6 and SAPK2 beta kinases.

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