Structural study of phenyl boronic acid derivatives as AmpC β-lactamase inhibitors
A small set of boronic acids acting as low nanomolar inhibitors of AmpC β-lactamase were designed and synthesized in the effort to improve affinity, pharmacokinetic properties, and to provide a valid lead compound. X-ray crystallography revealed the binar
Tondi, Donatella,Calò, Samuele,Shoichet, Brian K.,Costi, Maria Paola
supporting information; experimental part
p. 3416 - 3419
(2010/08/19)
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