Sulfone-mediated synthesis of polysubstituted pyridines
Base-mediated and/or palladium(0)-catalysed bis(allylation) of alkyl 2-(tolylsulfonyl)acetates gives 1,6-dienes, which upon ozonolytic cleavage of the double bonds and ammonolysis give 2,6-disubstituted pyridine-4-carboxylic esters. Decarboxylation of one
Craig, Donald,Henry, Gavin D.
p. 2559 - 2562
(2007/10/03)
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