852148-49-3

Basic information

• Product Name: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-
• Synonyms: (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-2-oxazolidinone;(S)-4-Benzyl-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)oxazolidin-2-one;(4R,5S)-Methyl 5-(4-(benzyloxy)phenyl)-5-((4-fluorophenyl)aMino)-4-((4S)-2-oxo-4-phenyltetrahydrofuran-3-carbonyl)pentanoate;2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-;Ezetimibe intermediate;2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-
• CAS NO: 852148-49-3
• Molecular Formula: C₂₁H₂₂FNO₄
• Molecular Weight: 371.41
• EINECS: 209-631-8
• Product Categories: Ezetimibe intermediates
• Mol File: 852148-49-3.mol

Chemical Properties

• Boiling Point: 574.5 °C at 760 mmHg
• Flash Point: 301.2 °C
• Appearance: /
• Density: 1.282 g/cm³
• Storage Temp.: 2-8°C
• PKA: 14.17±0.20(Predicted)
• CAS DataBase Reference: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(852148-49-3)
• EPA Substance Registry System: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(852148-49-3)

Safety Data

• Hazardous Substances Data: 852148-49-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)is used as a potential antimicrobial and antibacterial agent due to its oxazolidinone backbone, which is known for these properties. The presence of the 4-fluorophenyl and phenylmethyl substituents may enhance its biological activity, making it a candidate for further research and development in the pharmaceutical field.
Used in Medicinal Chemistry Research:
2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)is used as a subject of study in medicinal chemistry research to explore its potential applications and effects. The unique combination of functional groups and stereochemistry in 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)may offer insights into the design of new drugs with improved efficacy and selectivity.
Further research and testing are necessary to fully understand the potential uses and effects of this chemical, as its complex structure and chirality may influence its interactions with biological targets and its overall pharmacological profile.

Upstream product

• 852148-48-2 (4S)-4-benzyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-1,3-oxazolidin-2-one 
• 914777-33-6 1,9-bis(4-fluorophenyl)nonane-1,5,9-trione 
• 149437-76-3 5-(4-fluorophenyl)-5-oxopentanoic acid 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 1056188-47-6 C₁₆H₁₉FO₄ 

Downstream Products

• 852148-50-6 (4S)-4-benzyl-3-[(5S)-5-{[tert-butyl(dimethyl)silyl]oxy}-5-(4-fluorophenyl)pentanoyl]-1,3-oxazolidin-2-one 
• 1023283-10-4 C₄₁H₃₈BrFN₂O₆ 
• 913369-87-6 (4S)-3-[(2R,5S)-2-{(S)-anilino[2-(benzyloxy)-4-bromophenyl]methyl}-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-benzyl-1,3-oxazolidin-2-one 
• 852204-25-2 (3R,4S)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-(3,3'-dihydroxybiphenyl-4-yl)-1-phenylazetidin-2-one 
• 916169-47-6 C₃₇H₄₁BrFNO₃Si 
• 852204-51-4 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-{[tert-butyl(dimethyl)silyl]oxy}-4'-{(2S,3R)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-3-yl)-D-glucitol 
• 852204-60-5 (6S)-6-O-[tert-butyl(dimethyl)silyl]-6-C-(4'-{(2S,3R)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-oxo-1-phenylazetidin-2-yl}-3'-hydroxybiphenyl-3-yl)-1,2-O-(1-methylethylidene)-α-D-glucofuranose 
• 915215-36-0 (4S)-3-[(2R,5S)-2-[(S)-[2-(allyloxy)-4-bromophenyl](anilino)methyl]-5-{[tert-butyl(dimethyl)silyl]oxy}-5-(4-fluorophenyl)pentanoyl]-4-benzyl-1,3-oxazolidin-2-one 
• 914777-37-0 (3R,4S)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-[2-{[tert-butyl(dimethyl)silyl]oxy}-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-phenylazetidin-2-one 
• 852204-20-7 (3R,4S)-4-(4-bromo-2-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-1-phenylazetidin-2-one 
• 852204-16-1 (3R,4S)-4-[2-(allyloxy)-4-bromophenyl]-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-1-phenylazetidin-2-one 

Relevant articles and documents

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