85508-26-5

Basic information

• Product Name: 2-butylheptan-1-ol
• Synonyms: 2-butylheptan-1-ol;2-Butyl-1-heptanol;Einecs 287-451-9
• CAS NO: 85508-26-5
• Molecular Formula: C₁₁H₂₄O
• Molecular Weight: 172.30766
• EINECS: 287-451-9
• Mol File: 85508-26-5.mol

Chemical Properties

• Boiling Point: 229.7°C at 760 mmHg
• Flash Point: 93.8°C
• Appearance: /
• Density: 0.828g/cm³
• Vapor Pressure: 0.0132mmHg at 25°C
• Refractive Index: 1.437
• CAS DataBase Reference: 2-butylheptan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-butylheptan-1-ol(85508-26-5)
• EPA Substance Registry System: 2-butylheptan-1-ol(85508-26-5)

Safety Data

• Hazardous Substances Data: 85508-26-5(Hazardous Substances Data)

Usage

Uses

2-Butyl-1-heptanol is a useful synthesis reagent, a branched-chain alcohol.

InChI:InChI=1/C11H24O/c1-3-5-7-9-11(10-12)8-6-4-2/h11-12H,3-10H2,1-2H3

Upstream product

• 343598-18-5 2-(1-phenylthiobutyl)heptanal 
• 17510-50-8 1-trimethylsilanyloxy-hept-1-ene 
• 111-71-7 heptanal 

Relevant articles and documents

α-ALKYLATION AND α-ALKYLIDENATION OF CARBONYL COMPOUNDS BY O-SILYLATED ENOLATE PHENYLTHIOALKYLATION

For many reactions next to a carbonyl group, the use of O-silylated enolate chemistry offers improvements in yield and selectivity over the corresponding reactions of Group I metal enolates.In the case of α-alkylation of carbonyl compounds, Lewis acid (TiCl4 or ZnBr2) promoted phenylthioalkylation of O-silylated enolates 3 by α-chlorosulphides 4 (R3=H, Me, Prn, Pri, Bui, and Me3Si), followed by reductive sulphur removal by Raney nickel, 5->6, is found to be a reliable method for this synthetically important C-C bond forming step.An alternative sulphur elimination pathway via the sulphoxide, 5->7, allows the regio- and stereocontrolled α-alkylidenation of carbonyl compounds.The phenylthioalkylation reaction is applicable to ketones, aldehydes, esters, and lactones.

α-Alkylation and α-alkylidenation of carbonyl compounds: Lewis acid-promoted phenylthioalkylation of o-silylated enolates

The O-silylated enolates of ketones, aldehydes, esters, and lactones can be phenylthioalkylated in the presence of Lewis acids; reductive or oxidative sulphur-removal gives the regiospecifically α-alkylated or alkylidenated carbonyl compounds.