855183-03-8Relevant articles and documents
Synthesis of 5,6-dihydrophenanthridines via N,O-acetal TMS ethers
Lee, Won-Il,Jung, Jong-Wha,Jang, Jaebong,Yun, Hwayoung,Suh, Young-Ger
, p. 5167 - 5171 (2013/09/02)
A concise and high-yielding protocol for the synthesis of 5,6-dihydrophenanthridines is disclosed. The key feature includes a sequential reduction-cyclization reaction of N-acylcarbamates via N,O-acetal TMS ethers as a stable N-acyliminium ion precursor.
IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS
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Page/Page column 91-92, (2010/04/28)
The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.