855302-57-7

Basic information

• Product Name: 3-[(5-bromopyridin-2-yl)oxy]quinuclidine
• Synonyms: 3-[(5-bromopyridin-2-yl)oxy]quinuclidine;2-(2-(piperidin-1-yl)ethoxy)-5-bromopyridine
• CAS NO: 855302-57-7
• Molecular Formula: C₁₂H₁₅BrN₂O
• Molecular Weight: 283.1643
• Mol File: 855302-57-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[(5-bromopyridin-2-yl)oxy]quinuclidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(5-bromopyridin-2-yl)oxy]quinuclidine(855302-57-7)
• EPA Substance Registry System: 3-[(5-bromopyridin-2-yl)oxy]quinuclidine(855302-57-7)

Safety Data

• Hazardous Substances Data: 855302-57-7(Hazardous Substances Data)

Upstream product

• 53939-30-3 5-bromo-2-chloropyridine 
• 1619-34-7 3-quinuclidinol 

Relevant articles and documents

3-quinuclidinyl amino-substituted biaryl derivatives

Compounds of formula (I) wherein n is 0, 1, or 2; Y is O, S, —NH—, and —N-alkyl-; Ar1 is both 6-membered aromatic rings; Ar2 is 5- or 6-membered aromatic rings with a —NR8R9 group, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

3-Quinuclidinyl heteroatom bridged biaryl derivatives

Compounds of formula: or pharmaceutically acceptable salts, esters, amides, or prodrugs thereof, wherein: A and G are each independently N or N+—O?; m and n are each independently 0, 1, or 2; X1 and X3 are each independently O, S, and —N(R1)—; X2 is O, S, —N(R1)—, —N(Ar2)—, and —N(R2)C(O)—; Ar1 is a six-membered aromatic ring; Ar2 is cyclohexyl or a mono- or bicyclic aromatic ring, and R13 is hydrogen, alkyl, or halogen, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formulas (I) and (II) and methods for using such compounds and compositions.

3-Quinuclidinyl amino-substituted biaryl derivatives

Compounds of formula (I) wherein A is N or N+—O?; n is 0, 1, or 2; Y is O, S, —NH—, and —N-alkyl-; Ar1 is both 6-membered aromatic rings; Ar2 is 5- or 6-membered aromatic rings with a —NR8R9 group, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.