Enantioselective borane reduction of prochiral ketones catalyzed by a chloro-containing chiral β-amino alcohol
A chloro-containing chiral β-amino alcohol (S)-2-amino-3-(2-chlorophenyl)-1,1-diphenyl-1-propanol (1) was prepared from the related amino acid, which was synthesized via malonic ester method. As a catalyst for the enantioselective borane reduction of prochiral ketones, 1 is better than those that have a similar structure but have no halogen atom in the molecule.
Shen, Zong-Xuan,Lu, Jun,Zhang, Qing,Zhang, Ya-Wen
p. 2287 - 2289
(2007/10/03)
More Articles about upstream products of 855650-84-9