- Substituted piperidines as therapeutic compounds
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Described are compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R2, R3, W,and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II an
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- Substituted Piperidines as Renin Inhibitors
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Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines.
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Page/Page column 51
(2009/12/24)
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- Substituted piperidines as inhibitors of beta-secretase, cathepsin D, plasmepsin II and/or HIV protease
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Use of compounds of the general formula (I) or (II) and pharmaceutically acceptable salt thereof, in which R, R1, R2, R3, R4, Q, W, X and Z, n and m have the definitions illustrated in detail in the description,
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Page/Page column 19
(2008/12/07)
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- Substituted piperidines as therapeutic compounds
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Use of compounds of the general formula (1) and pharmaceutically acceptable salt thereof, in which R1, R2, R3, R4, W, X, Z and n have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.
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Page/Page column 32
(2008/12/08)
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- SUBSTITUTED 4-PHENYLPIPERIDINES
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The application relates to substituted 4-phenylpiperidines of the general formula and their salts, preferably their pharmaceutically acceptable salts, in which R2, R3, W and X have the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.
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Page/Page column 44
(2008/06/13)
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- ORGANIC COMPOUNDS
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The application relates to novel substituted piperidines of the general formula (I) in which R1, R2, R3, R4, W, X, Z, m and n are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.
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Page/Page column 37
(2010/02/15)
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- SUBSTITUTED PIPERIDINES
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SP-P2140 ATE - 132 - Abstract Novel substituted piperidines of the general formula (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are
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Page/Page column 29
(2010/11/24)
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- 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
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The application relates to novel substituted piperidines of the general formula (II) in which R1, R2', R2'', R4', X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.
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Page/Page column 48
(2008/06/13)
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- SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
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Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, W, X, Z and n as stated in Claim 1 have renin-inhibiting properties and can be used as medicines.
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Page/Page column 37
(2008/06/13)
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- ORGANIC COMPOUNDS
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Novel substituted piperidines of the general formulae (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent.
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Page/Page column 25
(2008/06/13)
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