858644-32-3

Basic information

• Product Name: 1-Boc-4-(3-oxo-3-phenylpropenyl)piperidine
• Synonyms: 1-Boc-4-(3-oxo-3-phenylpropenyl)piperidine;(E)-tert-butyl 4-(3-oxo-3-phenylprop-1-enyl)piperidine-1-carboxylate
• CAS NO: 858644-32-3
• Molecular Formula: C₁₉H₂₅NO₃
• Molecular Weight: 315.4067
• Mol File: 858644-32-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Boc-4-(3-oxo-3-phenylpropenyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-4-(3-oxo-3-phenylpropenyl)piperidine(858644-32-3)
• EPA Substance Registry System: 1-Boc-4-(3-oxo-3-phenylpropenyl)piperidine(858644-32-3)

Safety Data

• Hazardous Substances Data: 858644-32-3(Hazardous Substances Data)

Usage

Classification

Chemical compound

Use

Pharmaceutical research and development

Derivative of

Piperidine

Potential applications

Synthesis of new drugs and pharmaceuticals

Unique feature

Unique chemical structure

Importance

Potential use as a building block in the creation of new therapeutic agents

Additional uses

Medicinal chemistry and drug discovery

Future impact

Significant advancements in the pharmaceutical industry through further research and exploration of its properties and potential applications.

Upstream product

• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 3453-00-7 diethyl benzoylmethylphosphonate 

Downstream Products

• 301232-43-9 tert-butyl 4-(3-oxo-3-phenylpropyl)piperidine-1-carboxylate 

Relevant articles and documents

Quinoline derivatives as neurokinin receptor antagonists

The present invention relates to substituted quinoline hydrazides of Formula (I): wherein R1, R2, R3, R4, R5, X, Y and Z are defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.

QUINOLINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS

The present invention relates to substituted quinoline derivatives of Formula (I); wherein hal, n, A, formula (a) , R1, R2, R3, R4, R5 and R6 are defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.

Pyrrolidine modulators of chemokine receptor activity

The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.