Commercially available simple ionic liquids-promoted dehydrative carbon-carbon bond-forming reaction of diarylmethanols and triarylmethanols with pyrroles, thiophene, furan and indoles
Two commercially available simple ionic liquids, 1-ethyl-3-methylimidazolium trifluoromethanesulfonate and 1-ethyl-2,3-dimethylimidazolium trifluoromethansulfonate, effectively promote the solvent-free dehydrative carbon-carbon (C-C) bond-forming reaction
Organocatalyzed Friedel-Crafts arylation of benzylic alcohols
Electron-rich aromatic and heteroaromatic rings are functionalized directly with a variety of benzylic alcohols under mild conditions. The reaction is catalyzed by commercially available pentafluorophenylboronic acid, which is stable under ambient conditions and recoverable. The reaction itself is highly atom economical and produces water as the only byproduct. A Friedel-Crafts mechanism is proposed.
McCubbin, J. Adam,Krokhin, Oleg V.
supporting information; experimental part
p. 2447 - 2449
(2010/07/04)
METHOD FOR ESTABLISHING CC BONDS BETWEEN ELECTROPHILIC SUBSTRATES AND ? - NUCLEOPHILES IN NEUTRAL TO ALKALINE AQUEOUS OR ALCOHOLIC SOLVENTS WITHOUT USING A LEWIS OR BRONSTED ACID
The invention relates to a method for establishing carbon-carbon bonds by reacting electropohilic substrates that have a solvolysis rate kEtOH (25°C) > 10-6 s-1 and ? compounds. The method is characterized by generating the intermediary carbocations in neutral to alkaline aqueous or alcoholic solvents or solvent mixtures without using a Lewis or Br?nsted acid.
-
Page/Page column 16-17
(2008/06/13)
More Articles about upstream products of 861033-90-1