- Halogenation Reaction of S-Aryl-Ssulfoximide
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The reactions of the title free sulfoximide with N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) afforded the corresponding α-halogenated "free" sulfoximides in good yields.The α-bromination proceeded via a facile N-bromination followed by a bromine transfer reaction of the resulting N-bromosulfoximide.The NCS chlorination, in contrast, proceeded via direct α-chlorination, not via N-chlorination.However, in the presence of potassium carbonate or silica gel N-chlorination occured predominantly in the NCS chlorination.Keywords---1,2-benzisoxazole; halogenation; N-halosulfoximide; α-halo sulfoximide; rearrangement; induction period
- Yoshida, Toyokichi,Naruto, Shunsuke,Uno, Hitoshi,Nishimura, Haruki
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p. 1175 - 1182
(2007/10/02)
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