862178-11-8Relevant articles and documents
Small molecules with potent osteogenic-inducing activity in osteoblast cells
Han, Chun-Ya E.,Wang, Youping,Yu, Longchuan,Powers, David,Xiong, Xiaoling,Yu, Violeta,Nguyen, Yen,Jean Jr., David J. St.,Babij, Philip
supporting information; experimental part, p. 1442 - 1445 (2009/12/25)
A chemical screen of 45,000 compounds from a diverse collection led to the identification of two series of small molecules with potent osteogenic activity in mouse MC3T3-E1 osteoblast cells. The first chemical group was characterized by an amino benzothia
COMPOUNDS AND METHODS OF USE
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Page/Page column 63, (2008/06/13)
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.