A new approach to enantiopure C3-symmetric molecules
Chiral base chemistry has been used to create three chiral centres in one pot on a C3-symmetric substrate. The potential of this new approach to C3-symmetric molecules is exemplified by the creation of an enantiopure C3v-symmetric triol, triphosphane and tripyridine. A ruthenium complex of the last compound has been studied by X-ray crystallography.
Castaldi, M. Paola,Gibson, Susan E.,Rudd, Matthew,White, Andrew J. P.
Introduction of multiple elements of chirality around an aromatic core and an approach to enantiomerically pure C3-symmetric ligands
(Chemical Equation Presented) Chiral-base chemistry has been used to introduce multiple elements of chirality around an (arene)tricarbonylchromium(0) complex. Three stereogenic centers could be installed in one operation to synthesize a nonracemic chiral
Castaldi, M. Paola,Gibson, Susan E.,Rudd, Matthew,White, Andrew J. P.