- 1-(2H)-ISOQUINOLONE DERIVATIVE
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The present invention provides a compound having high antitumor activity, which is useful for therapeutic and preventive agents effective for proliferative diseases such as cancer; a production method thereof; an intermediate compound useful for such production; and a pharmaceutical composition comprising such a compound. The present invention provides a compound represented by the formula (1): wherein X represents an aryl group or heteroaryl group which may be substituted, Cy represents a 4- to 7-membered monocyclic heterocyclic ring or a 8- to 10-membered condensed heterocyclic ring which may be substituted, and Z represents O, S, or NRa; or a prodrug thereof; or a pharmaceutically acceptable salt thereof; and a pharmaceutical and a pharmaceutical composition which comprise the compound.
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Page/Page column 76
(2008/06/13)
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- 1-(2H)-ISOQUINOLONE DERIVATIVE
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The present invention provides: a compound represented by the following formula (I): [wherein Y 1 and Y 4 represent a hydrogen atom or a halogen atom; either one of Y 2 and Y 3 represents -NR 1 R 2 , and the other represents a hydrogen atom or a halogen a
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Page/Page column 56
(2010/11/24)
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