862874-75-7

Basic information

• Product Name: 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 1N-BOC 3-(4'-AMINOPHENOXY) PYRROLIDINE;3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 3-(4-aMinophenoxy)pyrrolidine-1-carboxylate;1-Boc-3-(4-aminophenoxy)-pyrrolidine
• CAS NO: 862874-75-7
• Molecular Formula: C15H22N2O3
• Molecular Weight: 278.35
• Product Categories: pharmacetical
• Mol File: 862874-75-7.mol

Chemical Properties

• Boiling Point: 416°C at 760 mmHg
• Flash Point: 205.4°C
• Appearance: /
• Density: 1.165g/cm³
• Vapor Pressure: 3.95E-07mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(862874-75-7)
• EPA Substance Registry System: 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(862874-75-7)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 862874-75-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used as a chemical intermediate for the synthesis of drugs with antibiotic and antiviral properties due to its functional groups that facilitate the development of such therapeutic agents.
Used in Medicinal Chemistry:
As a building block in the synthesis of organic compounds, 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is utilized for creating new pharmaceutical compounds, contributing to the advancement of medicinal chemistry and the discovery of novel treatments.
Used in Synthesis Process Protection:
The tert-butyl ester group in 3-(4-AMINO-PHENOXY)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is used to provide stability and protection to the functional groups during the synthesis of pharmaceutical compounds, ensuring the successful production of the desired therapeutic agents.

InChI:InChI=1/C15H22N2O3/c1-15(2,3)20-14(18)17-9-8-13(10-17)19-12-6-4-11(16)5-7-12/h4-7,13H,8-10,16H2,1-3H3

Relevant articles and documents

BISARYLUREA DERIVATIVES

The present invention relates to bisarylurea derivatives of formula (I), the use of the compounds of formula (I) as inhibitors of raf-kinase, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.

DIAMINOTHIAZOLES

The present invention is directed to novel diaminothiazoles of formula These compounds inhibit cyclin-dependent kinase 4 (Cdk4) and are selective against Cdk2 and Cdk1. These compounds and their pharmaceutically acceptable salts and esters have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors. This invention is also directed to pharmaceutical compositions containing such compounds and to methods of treating or controlling cancer, most particularly the treatment 6r control of breast, lung and colon and prostate tumors.