864248-52-2

Basic information

• Product Name: tert-butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate
• Synonyms: tert-butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate
• CAS NO: 864248-52-2
• Molecular Formula: C₁₉H₂₉N₃O₂
• Molecular Weight: 331.45246
• EINECS: -0
• Mol File: 864248-52-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate(864248-52-2)
• EPA Substance Registry System: tert-butyl 3-(4-benzylpiperazin-1-yl)azetidine-1-carboxylate(864248-52-2)

Safety Data

• Hazardous Substances Data: 864248-52-2(Hazardous Substances Data)

Upstream product

• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 2759-28-6 1-phenylmethylpiperazine 
• 193269-78-2 3-aminoazetidine-1-carboxylic acid tert-butyl ester 
• 10429-82-0 N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride 

Relevant articles and documents

NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3)

A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen or the like.]

SUBSTITUTED BENZIMIDAZOLONE DERIVATIVES, MEDICAMENTS COMPRISING THEM AND THEIR USE

The present invention relates to novel benzimidazolone derivatives of the general formula (I) in which the substituents R1, R2, R3, A1, A2, and B are as defined in claim 1, medicaments comprising these, and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent diseases.