The invention relates to substituted arylamide derivatives of the formula I, the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumours and/or diseases that are caused, mediated and/or propagated by angiogenesis. Compounds of the formula I are effective inhibitors of tyrosine kinases, in particular TIE-2 and VEGFR, and of Raf kinases.
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(2008/06/13)
PYRIDINAMIDE DERIVATIVE AS KINASE INHIBITORS
The invention relates to substituted arylamide derivatives of formula (I), to the production and use thereof for the production of a medicament for the treatment of diseases, in particular tumours and/or diseases which are provoked, transmitted and/or propagated by angiogenesis. Compounds of formula (I) are active inhibitors of tyrosine kinases, in particular TIE-2 and VEGFR, and the Raf-kinases.
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Page/Page column 52
(2010/02/14)
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