Studies toward the unique pederin family member psymberin: Full structure elucidation, two alternative total syntheses, and analogs
Two synthetic approaches to psymberin have been accomplished. A highly convergent first generation synthesis led to the complete stereochemical assignment and demonstrated that psymberin and irciniastatin A are identical compounds. This synthesis featured
Feng, Yu,Jiang, Xin,De Brabander, Jef K.
p. 17083 - 17093
(2013/01/15)
Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds
The invention relates to the synthesis and complete stereochemical assignments of cytotoxic compounds such as compound 28-a and its stereoisomers: The invention further provides processes for making the compounds, their synthetic intermediates, and for me
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Page/Page column 18
(2010/11/25)
Synthesis and complete stereochemical assignment of psymberin/irciniastatin A
We describe a concise and flexible synthetic avenue for the preparation of compounds with structures relevant to those proposed for the novel marine-derived differential cytotoxins psymberin and irciniastatin A. Our efforts led to their complete stereoche
Jiang, Xin,Garcia-Fortanet, Jorge,De Brabander, Jef K.
p. 11254 - 11255
(2007/10/03)
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