Gallium(III)-promoted halocyclizations of 1,6-diynes
Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts cyclizations, giving access to iodoi
Strom, Kyle R.,Impastato, Anna C.,Moy, Kenneth J.,Landreth, Adrian J.,Snyder, John K.
p. 2126 - 2129
(2015/05/13)
A highly regio- and stereoselective formation of bicyclo[4.2.0]oct-5-ene derivatives through thermal intramolecular [2 + 2] cycloaddition of allenes
(Chemical Equation Presented) Thermal [2 + 2] cycloaddition of allenes with an additional multiple bond is described. By simply heating the allenenes or allenynes having a three-atom tether in an appropriate solvent such as dioxane or DMF, the distal doub