Novel synthesis of 2-aryl and 2,3-disubstituted indoles by modified double elimination protocol
(Chemical Equation Presented) Syntheses of 2-aryl and 2,3-substituted indoles were realized by modified double elimination protocol. Under basic conditions, vinyl sulfones derived from the reaction of 2-aminobenzyl sulfone with benzaldehydes underwent cyclization and alkylation followed by elimination of sulfinic acid to afford 2,3-substituted indoles.
Babu, Govindarajulu,Orita, Akihiro,Otera, Junzo
p. 4641 - 4643
(2007/10/03)
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