869376-63-6Relevant articles and documents
POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS
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Page/Page column 4, (2009/03/07)
The present invention relates to high affinity compounds, able to bind CB1 and CB2 endocannabinoid receptors. The compounds of the invention find particular application as agents for pain therapy and/or anti-inflammatory and/or anti-
NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS
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Page/Page column 8-9, (2008/06/13)
The present invention relates to high affinity compounds, able to bind CB1 and CB2 endocannabinoid receptors. The compounds of the invention find particular application as agents for pain therapy and/or anti-inflammatory and/or anti-stress and/or anti-oxidising and/or hypotensive and/or immune suppressive therapy and/or anti-spastic activity in multiple sclerosis and/or anti-cancer.
Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors
Brizzi, Antonella,Brizzi, Vittorio,Cascio, Maria Grazia,Bisogno, Tiziana,Sirianni, Rossella,Marzo, Vincenzo Di
, p. 7343 - 7350 (2007/10/03)
Despite their different chemical structures, Δ9- tetrahydrocannabinol (THC) and anandamide (AEA) have common pharmacological properties. This study was aimed at finding new cannabinoid receptor ligands that overcome the instability of AEA and i