Synthesis of potential anticancer agents. Pyrido[4,3-b][1,4]oxazines and pyrido[4,3-b][1,4]thiazines
Hydrolysis of the chloro group of ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate (3) with formic acid gave the corresponding 4-hydroxypyridine 4. Catalytic hydrogenation of the nitro group of 4 gave the 5-amino-4-hydroxypyridine 5, which was reacte
Temple, Carroll,Wheeler, Glynn P.,Comber, Robert N.,Elliott, Robert D.,Montgomery, John A.
p. 1614 - 1619
(2007/10/02)
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