869941-99-1Relevant articles and documents
Synthesis and biological activity of some novel substituted quinazoline derivatives
Srivastav, Maneesh Kumar,Rajeeva,Salahuddin, Md.,Srinivasulu,Shanta Kumar
, p. 115 - 118 (2019/01/21)
A new series of 4-N-(substituted benzyl)-2-phenyl-N-propylquinazolines were synthesized. The structures of the synthesized compounds were confirmed by IR, 1H NMR, 13C NMR and mass spectral analysis. All the synthesized compounds were screened for their analgesic and anti-inflammatory activity. Among the synthesized compounds 5c, 5h and 5o exhibited significant analgesic activity at 60 and 90 minutes reading, while compounds 5g, 5k and 5l exhibited significant anti-inflammatory activity at 3rd and 4th hr reading.