2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization
Two types of adenosine receptor ligands were designed, i.e., 9H-purine and 1H-imidazo[4,5-c]pyridines, to obtain selective A2A antagonists, and we report here their synthesis and binding affinities for the four adenosine receptor subtypes Asub
Minetti, Patrizia,Tinti, Maria Ornella,Carminati, Paolo,Castorina, Massimo,Di Cesare, Maria Assunta,Di Serio, Stefano,Gallo, Grazia,Ghirardi, Orlando,Giorgi, Fabrizio,Giorgi, Luca,Piersanti, Giovanni,Bartoccini, Francesca,Tarzia, Giorgio
p. 6887 - 6896
(2007/10/03)
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