- A 3-L-peppermint propoxycyclohexyl propane -1,2-diol synthesis method
-
The invention relates to a synthesis method of 3-L-menthoxypropane-1,2-diol. The synthesis method comprises the steps of reacting menthol with 1,3-dihalo-glycerol acetate under a strong alkaline condition at a low temperature to generate 1-halo-2-acetoxy-
- -
-
Paragraph 0005; 0013
(2017/02/09)
-
- Method for producing 3-l-menthoxypropane-1,2-diol
-
A method for safely and efficiently producing high purity 3-l-menthoxypropane-1,2-diol and intermediates to be used in the method. As shown in the following reaction formula, 3-l-menthoxypropane-1,2-diol represented by the chemical formula (IV) is produced by adding l-menthol to a 1,2-epoxy-3-halogenopropane represented by the general formula (I) (wherein X represents a halogen atom) in an organic solvent in the presence of a Lewis acid, thereby producing a 1-halogeno-3-l-menthoxypropan-2-ol represented by the general formula (II), allowing the first intermediate to react with an alkali metal salt of an aliphatic carboxylic acid having from 1 to 5 carbon atoms to produce a 1-acyloxy-2-substituted-3-l-menthoxypropane represented by the general formula (III) and then hydrolyzing the second intermediate.
- -
-
-
- Process for producing 3-1-menthoxypropane-1,2-diol
-
A process for producing highly pure 3-1-menthoxypropane-1,2-diol safely and efficiently, and an intermediate to be used in the process. 3-1-menthoxypropane-1,2-diol represented by the chemical formula (IV) is produced by adding 1-menthol to a 1,2-epoxy-3-
- -
-
Page column 15
(2008/06/13)
-
- 3-Levo-Menthoxypropane-1,2-diol
-
3-l-Menthoxypropane-1,2-diol having the formula: STR1
- -
-
-
