Welcome to LookChem.com Sign In|Join Free

CAS

  • or

870998-13-3

CXCR3 Antagonist 6c is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

870998-13-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 870998-13-3 Structure

  • Basic information

    1. Product Name: CXCR3 Antagonist 6c
    2. Synonyms: CXCR3 Antagonist 6c
    3. CAS NO:870998-13-3
    4. Molecular Formula: C30H32Cl3N5O3
    5. Molecular Weight: 616.96578
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 870998-13-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 768.6±60.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.343±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 12.42±0.70(Predicted)
    10. CAS DataBase Reference: CXCR3 Antagonist 6c(CAS DataBase Reference)
    11. NIST Chemistry Reference: CXCR3 Antagonist 6c(870998-13-3)
    12. EPA Substance Registry System: CXCR3 Antagonist 6c(870998-13-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 870998-13-3(Hazardous Substances Data)

870998-13-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 870998-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,9,9 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 870998-13:
(8*8)+(7*7)+(6*0)+(5*9)+(4*9)+(3*8)+(2*1)+(1*3)=223
223 % 10 = 3
So 870998-13-3 is a valid CAS Registry Number.

870998-13-3Downstream Products

870998-13-3Relevant articles and documents

SUBSTITUTED [1,4]-DIAZEPANES AS CXCR3 ANTAGONISTS AND THEIR USE IN THE TREATMENT OF INFLAMMATORY DISORDERS

-

Page/Page column 20; 49, (2008/06/13)

CXCR3 inhibitors of formula are disclosed. Inhibition of CXCR3 activation is useful for treating disorders resulting from CXCR3 -associated T-cell mediated function, such as inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis and diabetes

Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists

Cole, Andrew G.,Stroke, Ilana L.,Brescia, Marc-Raleigh,Simhadri, Srilatha,Zhang, Joan J.,Hussain, Zahid,Snider, Michael,Haskell, Christopher,Ribeiro, Sofia,Appell, Kenneth C.,Henderson, Ian,Webb, Maria L.

, p. 200 - 203 (2007/10/03)

The identification and evaluation of aryl-[1,4]diazepane ureas as functional antagonists of the chemokine receptor CXCR3 are described. Specific examples exhibit IC50 values of ～60 nM in a calcium mobilization functional assay, and dose-dependently inhibit CXCR3 functional response to CXCL11 (interferon-inducible T-cell α chemoattractant/I-TAC) as measured by T-cell chemotaxis, with a potency of approximately 100 nM.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 870998-13-3