- Synthesis and evaluation of 3-halocyclophosphamides and analogous compounds as novel anticancer 'pro-prodrugs'
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3-Fluoro-, 3-chloro-, and 3-bromocyclophosphamide were prepared from the reaction of trifluoromethylhypofluorite, sodium hypochlorite, and bromine with the anticancer drug cyclophosphamide. Treatment of cis-, and trans-4-phenylcyclophosphamide and 5,6-ben
- Zon,Ludeman,Ozkan,Chandrasegaran,Hammer,Dickerson,Mizuta,Egan
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p. 687 - 691
(2007/10/02)
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