Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group
Histone deacetylases (HDAC) are promising targets for cancer chemotherapy. HDAC inhibitors are thought to act in part by disrupting normal cell cycle regulation, resulting in apoptosis and/or differentiation of transformed cells. Several HDAC inhibitors,
Wu, Tom Y. H.,Hassig, Christian,Wu, Yiqin,Ding, Sheng,Schultz, Peter G.
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(2007/10/03)
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