- Synthesis of new pyrimidine derivatives with evaluation of their anti-inflammatory and analgesic activities
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5-Formyl-6-aminopyrimidine-2,4-(1H, 3H)-dione (2) has been previously prepared from compound 1. Cyclocondensation reaction of compound 2 with cyanoacetamide gave substituted pyridopyrimidine 3. Also, compound 2 was condensed with p-amino acetophenone and
- Nofal, Zienab M.,Fahmy, Hoda H.,Zarea, Eman S.,El-Eraky, Wafaa
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scheme or table
p. 507 - 517
(2012/01/31)
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- SYNTHESIS OF 5-FORMYL-2,4,6-TRISUBSTITUTED PYRIMIDINES
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A facile synthesis of 5-formyl-2,4,6-trisubstituted pyrimidines bearing amino and hydroxy groups is described.The Vilsmeier reagent, under mild conditions, gives good yields of products without accompanying chlorination of hydroxy groups.
- Delia, Thomas J.,Otteman, Ronald
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p. 1805 - 1809
(2007/10/02)
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- SYNTHESIS OF PYRIDOPYRIMIDINES ON THE BASIS OF 5-FORMYL-6-AMINOURACILS
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2,4-Dioxo-1,2,3,4-tetrahydropyridopyrimidines, the structures of which were proved by the PMR and the IR spectra, are formed in the condensation of mono- and di-N-alkyl-5-formyl-6-aminouracils with cyanoacetic acid and its esters, acetoacetic ester
- Cherdantseva, N. M.,Nesterov, V. M.,Safonova, T. S.
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p. 674 - 677
(2007/10/02)
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