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4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is a chlorinated derivative of dihydroisoindolone, a heterocyclic compound with the molecular formula C8H7ClNO2. It is a versatile chemical compound used as a precursor or intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, dyes, pigments, and polymer additives.

871723-37-4

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871723-37-4 Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is used as a precursor or intermediate in the synthesis of pharmaceuticals for its potential biological activities, making it of interest to researchers in medicinal chemistry and drug discovery.
Used in Agrochemical Industry:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is used as a precursor or intermediate in the synthesis of agrochemicals, contributing to the development of new and effective crop protection products.
Used in Dye and Pigment Industry:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is used as a building block in the production of dyes and pigments, offering a wide range of color options and properties for various applications.
Used in Polymer Additive Industry:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is used as a precursor or intermediate in the synthesis of polymer additives, enhancing the performance and properties of polymer materials.
Used in Material Science Research:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE has potential uses in the development of new materials, serving as a building block for the synthesis of novel chemical compounds in research laboratories.
Used in Chemical Synthesis:
4-CHLORO-2,3-DIHYDRO-ISOINDOL-1-ONE is used as a versatile intermediate in various industrial processes, facilitating the synthesis of a wide range of organic compounds for different applications.

Check Digit Verification of cas no

The CAS Registry Mumber 871723-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,7,2 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 871723-37:
(8*8)+(7*7)+(6*1)+(5*7)+(4*2)+(3*3)+(2*3)+(1*7)=184
184 % 10 = 4
So 871723-37-4 is a valid CAS Registry Number.

871723-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-2,3-dihydroisoindol-1-one

1.2 Other means of identification

Product number -
Other names 4-chloro-2,3-dihydro-isoindol-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:871723-37-4 SDS

871723-37-4Downstream Products

871723-37-4Relevant articles and documents

HPK1 ANTAGONISTS AND USES THEREOF

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Paragraph 1316; 1319, (2021/03/19)

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.

Pd-Catalyzed C(sp2)?H Alkoxycarbonylation of Phenethyl- and Benzylamines with Chloroformates as CO Surrogates

Andrade-Sampedro, Paula,Matxain, Jon M.,Correa, Arkaitz

supporting information, p. 5782 - 5789 (2021/03/06)

The site-selective functionalization of C?H bonds within a complex molecule remains a challenging task of capital synthetic importance. Herein, an unprecedented Pd-catalyzed C(sp2)?H alkoxycarbonylation of phenylalanine derivatives and other amines featuring picolinamide as the directing group (DG) is reported. This oxidative coupling is distinguished by its scalability, operational simplicity, and avoids the use of toxic carbon monoxide as the C1 source. Remarkably, the easy cleavage of the DG enables the efficient assembly of isoindolinone compounds. Density Functional Theory calculations support a PdII/PdIV catalytic cycle.

Palladium-Catalyzed Direct C-H Carbonylation of Free Primary Benzylamines: A Synthesis of Benzolactams

Zhang, Chunhui,Ding, Yongzheng,Gao, Yuzhen,Li, Shangda,Li, Gang

supporting information, p. 2595 - 2598 (2018/05/22)

A protocol for palladium-catalyzed C-H carbonylation of readily available free primary benzylamines using NH2 as the chelating group under an atmospheric pressure of CO has been achieved, providing a general, atom- and step-economic approach to

HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS

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Page/Page column 72, (2009/03/07)

The present invention related to novel heterocyclic amide compounds of Formula 1: as disclosed herein or a pharmaceutically accept able salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosedare compositions comprising said compounds, and methods for using said compounds for treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease

COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

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Page/Page column 561, (2010/02/15)

This invention relates to compounds of the Formula (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF-α or combinations thereof.

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