The present invention relates to compounds useful as inhibitors of protein kinases, containing a cysteine residue in the ATP binding site. The invention further provides for pharmaceutically acceptable compositions comprising therapeutically effective amounts of one or more of the protein kinase inhibitor compounds and methods of using said compositions in the treatment of cancers and carcinomas.
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Paragraph 00777
(2014/09/29)
5-ALKYLOXY-INDOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPY
The present invention relates to derivatives of 5-alkyloxy-indolin-2-one, their method of production and their therapeutic applications. These novel derivatives have affinity and selectivity for the V2 receptors of vasopressin (“V2 receptors”) and can therefore constitute active principles of pharmaceutical compositions.
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Page/Page column 10
(2010/04/23)
DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF
The invention relates to compounds of the general formula (I), wherein R stands for nitro group or -COOR1 group, wherein R1 stands for hydrogen atom or for C1-4 straight or branched alkyl group, R2 stands for hy
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Page/Page column 7
(2008/06/13)
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