873055-16-4 Usage
Aromatic amine
1H-Indol-6-amine,3-(1-methylethyl)-(9CI) is classified as an aromatic amine, meaning it contains a nitrogen atom bonded to an aromatic ring.
Indole derivative
1H-Indol-6-amine,3-(1-methylethyl)-(9CI) is a derivative of indole, a bicyclic aromatic organic compound consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring.
Amine functional group
The compound contains an amine functional group (-NH2) attached to the 6th carbon atom of the indole ring, which can participate in various chemical reactions.
3-(1-methylethyl) substituent
A 3-(1-methylethyl) substituent, which is an isopropyl group (-CH(CH3)2), is attached to the indole ring, further modifying the chemical properties of the compound.
Organic synthesis and pharmaceutical research
1H-Indol-6-amine,3-(1-methylethyl)-(9CI) is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities and therapeutic properties.
Safety precautions
It is important to handle 1H-Indol-6-amine,3-(1-methylethyl)-(9CI) with caution and follow proper safety protocols when working with it, as it may have potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 873055-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,0,5 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 873055-16:
(8*8)+(7*7)+(6*3)+(5*0)+(4*5)+(3*5)+(2*1)+(1*6)=174
174 % 10 = 4
So 873055-16-4 is a valid CAS Registry Number.
873055-16-4Relevant articles and documents
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
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Page/Page column 72, (2012/12/14)
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES
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, (2012/04/23)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
