87549-36-8

Basic information

• Product Name: MR 897
• Synonyms: MR 897;2-Methyl-2-[4-(acetylamino)phenoxy]-4H-1,3-benzodioxin-4-one
• CAS NO: 87549-36-8
• Molecular Formula: C17H15NO5
• Molecular Weight: 313.3
• Mol File: 87549-36-8.mol

Chemical Properties

• Boiling Point: 590°C at 760 mmHg
• Flash Point: 310.6°C
• Appearance: /
• Density: 1.328g/cm³
• Vapor Pressure: 6.73E-14mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: MR 897(CAS DataBase Reference)
• NIST Chemistry Reference: MR 897(87549-36-8)
• EPA Substance Registry System: MR 897(87549-36-8)

Safety Data

• Hazardous Substances Data: 87549-36-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
MR 897 is used as a prodrug for the combined therapy of Acetylsalicylic Acid and Paracetamol. It offers the benefits of both drugs in a single molecule, providing effective pain relief and anti-inflammatory action.
Used in Drug Delivery Systems:
MR 897 is used as a carrier for targeted drug delivery. Its unique structure allows for the controlled release of the active metabolites, acetylsalicylic acid, salicylic acid, and paracetamol, ensuring optimal therapeutic effects and minimizing side effects.
Used in Cosmetic Industry:
MR 897 is used as an active ingredient in cosmetic products for its anti-inflammatory and pain-relieving properties. It can be incorporated into creams, lotions, and other formulations to provide relief from skin inflammation and discomfort.
Used in Food and Beverage Industry:
MR 897 can be used as a natural preservative and flavor enhancer in food and beverage products. Its anti-inflammatory and pain-relieving properties can also be beneficial in functional foods and beverages targeting health and wellness.

InChI:InChI=1/C17H15NO5/c1-11(19)18-12-7-9-13(10-8-12)21-17(2)22-15-6-4-3-5-14(15)16(20)23-17/h3-10H,1-2H3,(H,18,19)

Upstream product

• 103-90-2 4-acetaminophenol 
• 50-78-2 aspirin 

Relevant articles and documents

Synthesis and Hydrolysis of New Aspirin- and Triflusal-Derived Ortho Esters and Anhydrides

Ten new 2-substituted 2-methyl-2-oxy-4H-1,3-benzodioxin-4-ones, 4a-i and 6, have been synthesized and their rate constants of pseudo-first-order non enzymatic hydrolysis determined.One of the compounds, 2-(2-acetoxybenzoyloxy)-2-methyl-4H-1,3-benzodioxin-4-one, 6, is a new anhydride of aspirin.The analogous triflusal derivative, 10, has also been synthesized.