875573-42-5Relevant articles and documents
PRODUCTION METHOD OF BENZOTHIAZOLE DERIVATIVE
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Paragraph 0320; 0325; 0360-0362, (2020/06/18)
PROBLEM TO BE SOLVED: To provide: a production method of a benzothiazole derivative; as well as a production method of a polymerizable compound produced from the benzothiazole derivative; a polymerizable composition including the polymerizable compound; a polymer obtained by polymerizing the polymerizable composition; and an optical isomer utilizing the polymer. SOLUTION: A production method of a compound represented by the following general formula (III) is provided, and also a production method of a polymerizable compound produced from the compound represented by the general formula (III), a polymerizable composition, a polymer obtained by polymerizing the polymerizable composition, and an optical isomer utilizing the polymer are provided. When the polymerizable composition containing the compound is polymerized and the obtained film-like polymer is irradiated with ultraviolet light, change of color and change of phase difference scarcely take place. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT
COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS
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Paragraph 00282, (2014/12/12)
Described herein are compounds and compositions for treating drug resistant and persistent tuberculosis. Also described herein is a method of screening for identifiying biofilm formation inhibitors.
Design, synthesis, and biological activity of novel factor Xa inhibitors: Improving metabolic stability by S1 and S4 ligand modification
Komoriya, Satoshi,Kobayashi, Shozo,Osanai, Ken,Yoshino, Toshiharu,Nagata, Tsutomu,Haginoya, Noriyasu,Nakamoto, Yumi,Mochizuki, Akiyoshi,Nagahara, Takayasu,Suzuki, Makoto,Shimada, Takashi,Watanabe, Kengo,Isobe, Yumiko,Furugoori, Taketoshi
, p. 1309 - 1330 (2007/10/03)
Serine protease factor xa (fXa) inhibitor 1 showed good ex vivo anti-fXa activity upon oral administration in rats. However, it has been revealed that 1 had low metabolic stability against human liver microsomes. To improve the metabolic stability, we att