Synthesis of 131I-labeled glucose-conjugated inhibitors of 06-methylguanine-DNA methyltransferase (MGMT) and comparison with nonconjugated inhibitors as potential tools for in vivo MGMT imaging
O6-Substituted guanine derivatives are powerful agents used for tumor cell sensitization by inhibition of the DNA repair enzyme O 6-methylguanine-DNA methyltransferase (MGMT). To provide targeted accumulation of MGMT inhibitors in tu
Mühlhausen, Ute,Schirrmacher, Ralf,Piel, Markus,Lecher, Bernd,Briegert, Manuela,Piee-Staffa, Andrea,Kaina, Bernd,R?sch, Frank
p. 263 - 272
(2007/10/03)
More Articles about upstream products of 875584-27-3