875664-27-0

Basic information

• Product Name: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE
• Synonyms: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE;BUTTPARK 154\11-38;2-Amino-3-bromo-5-fluorobenzotrifluoride, 98%;Benzenamine,2-bromo-4-fluoro-6-(trifluoromethyl)-;2-Bromo-4-fluoro-6-(trifluoromethyl)benzenamine
• CAS NO: 875664-27-0
• Molecular Formula: C₇H₄BrF₄N
• Molecular Weight: 258.01
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 875664-27-0.mol

Chemical Properties

• Boiling Point: 212.553 °C at 760 mmHg
• Flash Point: 82.349 °C
• Appearance: /
• Density: 1.772 g/cm³
• Vapor Pressure: 0.172mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(875664-27-0)
• EPA Substance Registry System: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(875664-27-0)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: 6.1
• Hazardous Substances Data: 875664-27-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is used as a key intermediate in the synthesis of various organic compounds for [application reason]. Its unique structure, featuring a bromine, a fluorine, and a trifluoromethyl group, makes it a valuable building block in the creation of complex molecules.
Used in Research Environments:
In the field of scientific research, 2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is used as a reagent or a precursor for [application reason]. Its properties and reactivity are studied to understand its potential applications in the development of new materials and compounds.
Used in Pharmaceutical Industry:
2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is used as a starting material for the synthesis of pharmaceutical compounds for [application reason]. Its presence in the molecular structure can influence the activity and selectivity of the resulting drug molecules, making it an important component in drug discovery and development processes.
Used in Chemical Industry:
In the chemical industry, 2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is used as a specialty chemical for [application reason]. Its unique combination of functional groups can be exploited to produce a range of products with specific properties and applications in various sectors.

InChI:InChI=1/C7H4BrF4N/c8-5-2-3(9)1-4(6(5)13)7(10,11)12/h1-2H,13H2

Upstream product

• 393-39-5 4-fluoro-2-(trifluoromethyl)aniline 

Downstream Products

• 1027511-90-5 1,2-dibromo-5-fluoro-3-(trifluoromethyl)benzene 
• 1027511-98-3 1-bromo-2-chloro-5-fluoro-3-(trifluoromethyl)benzene 

Relevant articles and documents

QUINOXALINE DERIVATIVES

The present invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

SUBSTITUTED TRIAZOLO QUINOXALINE DERIVATIVES

The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured. The variables shown in Formula AA are as defined in the claims. The compounds of formula AA are NLRP3 activity modulators and, as such, can be used in the treatment of metabolic disorders (e.g. Type 2 diabetes, atherosclerosis, obesity or gout), a disease of the central nervous system (e.g. Alzheimer's disease, multiple sclerosis, Amyotrophic Lateral Sclerosis or Parkinson's disease), lung disease (e.g. asthma, COPD or pulmonary idiopathic fibrosis), liver disease (e.g. NASH syndrome, viral hepatitis or cirrhosis), pancreatic disease (e.g. acute pancreatitis or chronic pancreatitis), kidney disease (e.g. acute kidney injury or chronic kidney injury), intestinal disease (e.g. Crohn's disease or Ulcerative Colitis), skin disease (e.g. psoriasis), musculoskeletal disease (e.g. scleroderma), a vessel disorder (e.g. giant cell arteritis), a disorder of the bones (e.g. osteoarthritis, osteoporosis or osteopetrosis disorders), eye disease (e.g. glaucoma or macular degeneration), a disease caused by viral infection (e.g. HIV or AIDS), an autoimmune disease (e.g. Rheumatoid Arthritis, Systemic Lupus Erythematosus or Autoimmune Thyroiditis), cancer or aging.