875820-12-5Relevant articles and documents
CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST
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Paragraph 0093-0095, (2020/03/24)
The present invention relates to a compound shown in formula (II) or a pharmaceutically acceptable salt thereof and an application of the same in preparing a drug for treating a disease related to angiotensin II receptor type 2 (AT2R).(II)
Enantioselective palladium-catalyzed insertion of α-aryl-α- diazoacetates into the O-H bonds of phenols
Xie, Xiu-Lan,Zhu, Shou-Fei,Guo, Jun-Xia,Cai, Yan,Zhou, Qi-Lin
supporting information, p. 2978 - 2981 (2014/04/03)
A palladium-catalyzed asymmetric O-H insertion reaction was developed. Palladium complexes with chiral spiro bisoxazoline ligands promoted the insertion of α-aryl-α-diazoacetates into the O-H bond of phenols with high yield and excellent enantioselectivity under mild reaction conditions. This palladium-catalyzed asymmetric O-H insertion reaction provided an efficient and highly enantioselective method for the preparation of synthetically useful optically active α-aryl-α-aryloxyacetates.