1-Aryl-3-(2,4-dimethyl-5-ethoxycarbonyl-3-pyrrolyl)-5-oxopyrazoles were obtained by condensation of ethyl β-(2,4-dimethyl-5-ethoxycarbonyl-3-pyrrolyl)-β-ketopropionate with arylhydrazines.Electron-donor substituents in the aromatic ring of the arylhydrazines accelerate the cyclization of the intermediate hydrazones, whereas electron-acceptor substituents hinder cyclization.
Zhestkov, V.P.,Voronin, V.G.,Portnov, Yu.N.
p. 863 - 867
(2007/10/02)
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