- TYK2 INHIBITORS AND USES THEREOF
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The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
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- METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES
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The present invention relates to methods o f preparing substituted triazolopyridine compounds of general formula (I) as described and defined herein, as well as to intermediate compounds useful in the preparation of said compounds.
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Page/Page column 72; 73
(2014/02/15)
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- SUBSTITUTED TRIAZOLOPYRIDINES AND THEIR USE AS TTK INHIBITORS
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The present invention relates to substituted triazolopyndine compounds of general formula (I) : in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
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Page/Page column 97; 98; 99
(2013/07/05)
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- Creation of superior carboxyfluorescein dyes by blocking donor-excited photoinduced electron transfer
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(Chemical Equation Presented) Carboxyfluoresceins are widely utilized as fluorescence labeling reagents, but we recently found that their emission intensity is markedly decreased after esterification. On the basis of our hypothesis that the fluorescence d
- Mineno, Tomoko,Ueno, Tasuku,Urano, Yasuteru,Kojima, Hirotatsu,Nagano, Tetsuo
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p. 5963 - 5966
(2007/10/03)
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