Suzuki-miyaura cross-coupling of heteroaryl halides and arylboronic acids in continuous flow
General continuous-flow conditions for the Suzuki-Miyaura cross-coupling of heteroaryl halides and (hetero)arylboronic acids have been developed. A wide range of heterobiaryl products is obtained in excellent yields (20 examples) employing low catalyst loadings (0.05-1.5 mol % Pd).
Noel, Timothy,Musacchio, Andrew J.
supporting information; experimental part
p. 5180 - 5183
(2011/12/15)
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