Ternary nylon-3 copolymers as host-defense peptide mimics: Beyond hydrophobic and cationic subunits
Host-defense peptides (HDPs) are produced by eukaryotes to defend against bacterial infection, and diverse synthetic polymers have recently been explored as mimics of these natural peptides. HDPs are rich in both hydrophobic and cationic amino acid residu
Chakraborty, Saswata,Liu, Runhui,Hayouka, Zvi,Chen, Xinyu,Ehrhardt, Jeffrey,Lu, Qin,Burke, Eileen,Yang, Yiqing,Weisblum, Bernard,Wong, Gerard C. L.,Masters, Kristyn S.,Gellman, Samuel H.
supporting information
p. 14530 - 14535
(2015/01/08)
4-Iodomethylazetidin-2-one
Disclosed is a process for preparing 7-(1-hydroxethyl)-3-(2-aminoethylthio)-1-carbadethiaceph-3-em-3-carboxylic acid and its pharmaceutically acceptable salts and esters (I) by total synthesis starting with L-aspartic acid and proceeding via intermediates II and IIa (4-iodomethylazetidin-2-one): STR1
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(2008/06/13)
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