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4-AMINOMETHYL QUINOLINE HYDROCHLORIDE is a chemical compound characterized by a quinoline ring system with an attached amino group and a methyl group. It serves as a crucial building block in the synthesis of pharmaceuticals and agrochemicals, and is recognized for its antimalarial, antitumor, and potential neurodegenerative disease-treating properties, making it a significant intermediate in the creation of biologically active compounds for both medical and agricultural applications.

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  • 878778-84-8 Structure
  • Basic information

    1. Product Name: 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE
    2. Synonyms: 4-AMinoMethyl quinoline 2HCl;4-Quinolinemethanamine hydrochloride;C-Quinolin-4-yl-methylamine dihydrochloride;Quinolin-4-ylmethanamine dihydrochloride;(4-Quinolinylmethyl)amine dihydrochloride
    3. CAS NO:878778-84-8
    4. Molecular Formula: C10H10N2HCl
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 878778-84-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 349.1°C at 760 mmHg
    3. Flash Point: 164.9°C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 3.39E-05mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE(878778-84-8)
    12. EPA Substance Registry System: 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE(878778-84-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 878778-84-8(Hazardous Substances Data)

878778-84-8 Usage

Uses

Used in Pharmaceutical Industry:
4-AMINOMETHYL QUINOLINE HYDROCHLORIDE is used as a key intermediate in the synthesis of various drugs for its antimalarial and antitumor properties, contributing to the development of new medications that target these conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE is utilized as a component in the production of agrochemicals, leveraging its chemical structure to create compounds that can address agricultural challenges.
Used in Neurodegenerative Disease Research:
4-AMINOMETHYL QUINOLINE HYDROCHLORIDE is used as a potential therapeutic agent in the research and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's, due to its studied effects that may help in managing these conditions.
Used in Drug Development:
As a compound with demonstrated biological activity, 4-AMINOMETHYL QUINOLINE HYDROCHLORIDE is used in drug development for its potential to be incorporated into new pharmaceutical formulations that can treat a range of diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 878778-84-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,7,7 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 878778-84:
(8*8)+(7*7)+(6*8)+(5*7)+(4*7)+(3*8)+(2*8)+(1*4)=268
268 % 10 = 8
So 878778-84-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2.ClH/c11-7-8-5-6-12-10-4-2-1-3-9(8)10;/h1-6H,7,11H2;1H

878778-84-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name quinolin-4-ylmethanamine,dihydrochloride

1.2 Other means of identification

Product number -
Other names 4-AMINOMETHYL QUINOLINE 2HCL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:878778-84-8 SDS

878778-84-8Upstream product

878778-84-8Downstream Products

878778-84-8Relevant articles and documents

Fabrication of ω-Transaminase@Metal-Organic Framework Biocomposites for Efficiently Synthesizing Benzylamines and Pyridylmethylamines

Yu, Jinhai,Zong, Weilu,Ding, Yingying,Liu, Junzhong,Chen, Lina,Zhang, Hongjuan,Jiao, Qingcai

, p. 380 - 390 (2021/11/05)

In this study, ten ω-transaminases (ω-TAs) have been investigated to efficiently catalyze the synthesis of twenty-four functionalized benzylamines and pyridylmethylamines. We optimized the reactions, screened suitable amino donors and compared ω-transaminases activities for all aromatic aldehyde substrates. Under the optimized conditions, eighteen aromatic amines have been obtained with 60.4%–96.6% conversions and isolated only via simple extraction and recrystallization with 18.5%–81% yields on a preparative scale. Furthermore, we first immobilized the Bm-STA onto the MOFs via the physical adsorption to overcome the limitation of free enzyme and improve their industrial applications. The obtained Bm-STA/UiO-66-NH2 composites exhibited not only high enzymes loading (80.4 mg g?1) and enzyme activity recovery (95.8%), but also the better reusability, storage stability, pH stability and the tolerance to acetone and DMF.

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