878805-74-4

Basic information

• Product Name: 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone
• Synonyms: 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone
• CAS NO: 878805-74-4
• Molecular Formula: C₁₃H₁₉BF₃NO₃
• Molecular Weight: 305.1010696
• Mol File: 878805-74-4.mol

Chemical Properties

• Boiling Point: 341.0±52.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.57±0.40(Predicted)
• CAS DataBase Reference: 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone(878805-74-4)
• EPA Substance Registry System: 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone(878805-74-4)

Safety Data

• Hazardous Substances Data: 878805-74-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,2,2-Trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone is used as a building block in organic synthesis for the creation of pharmaceuticals and other organic compounds. Its unique structure allows for the development of new molecules with specific properties and functions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, this compound serves as a key intermediate for the synthesis of potential drug candidates. Its incorporation into pharmaceuticals can enhance the therapeutic efficacy and selectivity of the resulting medications.
Used in Materials Science:
2,2,2-Trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone may also find applications in materials science, where the unique properties of fluorinated compounds, such as their high electronegativity and reactivity, can be leveraged to develop novel materials with specific characteristics.
Safety Precautions:
Due to the complex structure and potential reactivity of 2,2,2-trifluoro-1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone, it is essential to handle and use this compound with appropriate safety measures. Trained professionals should guide its application to ensure safe and effective utilization in various industries.

Upstream product

• 878805-73-3 1-(2,2,2-trifluoroacetyl)-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 878805-75-5 t-butyl ((1S)-1-{4-[1-(trifluoroacetyl)-1,2,3,6-tetrahydropyridin-4-yl]phenyl}ethyl)carbamate 

Relevant articles and documents

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.