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2-Difluoromethyl-phenylboronic acid is a chemical compound characterized by the molecular formula C7H7BF2O2. It is a versatile building block in organic synthesis, particularly for the development of pharmaceutical and agrochemical compounds. The presence of the boronic acid functional group endows the compound with the ability to engage in Suzuki-Miyaura cross-coupling reactions, which are pivotal for the creation of carbon-carbon bonds. The incorporation of the difluoromethyl group imparts distinctive properties to the molecule, rendering it an invaluable asset in drug discovery and material science. Furthermore, this compound is under investigation for its potential anti-cancer properties, marking it as a significant subject in the realm of medicinal chemistry.

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  • 879275-70-4 Structure
  • Basic information

    1. Product Name: 2-Difluoromethyl-phenylboronic acid
    2. Synonyms: 2-Difluoromethyl-phenylboronic acid
    3. CAS NO:879275-70-4
    4. Molecular Formula: C7H7BF2O2
    5. Molecular Weight: 171.9370864
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 879275-70-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 301.1°C at 760 mmHg
    3. Flash Point: 135.9°C
    4. Appearance: /
    5. Density: 1.27g/cm3
    6. Vapor Pressure: 0.000476mmHg at 25°C
    7. Refractive Index: 1.479
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-Difluoromethyl-phenylboronic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Difluoromethyl-phenylboronic acid(879275-70-4)
    12. EPA Substance Registry System: 2-Difluoromethyl-phenylboronic acid(879275-70-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 879275-70-4(Hazardous Substances Data)

879275-70-4 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Difluoromethyl-phenylboronic acid serves as a key building block in the synthesis of various pharmaceutical and agrochemical compounds. Its unique structure and functional groups facilitate the development of novel molecules with enhanced properties and therapeutic potential.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Difluoromethyl-phenylboronic acid is utilized as a versatile intermediate for the creation of complex organic molecules. Its ability to participate in Suzuki-Miyaura cross-coupling reactions allows for the efficient formation of carbon-carbon bonds, which is crucial for the synthesis of a wide range of organic compounds.
Used in Drug Discovery:
2-Difluoromethyl-phenylboronic acid is employed as a valuable tool in drug discovery, where its unique properties and reactivity contribute to the design and synthesis of new drug candidates. Its potential role in the development of anti-cancer agents makes it a promising candidate for further research and exploration in medicinal chemistry.
Used in Material Science:
In the realm of material science, 2-Difluoromethyl-phenylboronic acid is leveraged for its distinctive properties, which can be harnessed to develop new materials with specific characteristics. Its reactivity and functional groups make it a suitable candidate for the synthesis of advanced materials with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 879275-70-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,9,2,7 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 879275-70:
(8*8)+(7*7)+(6*9)+(5*2)+(4*7)+(3*5)+(2*7)+(1*0)=234
234 % 10 = 4
So 879275-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BF2O2/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4,7,11-12H

879275-70-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(difluoromethyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names PC1611

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:879275-70-4 SDS

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